Animal Models for Neovascular Glaucoma

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Animal models have been a valuable tool in advancing the understanding of neovascular glaucoma (NVG) and in the development of new treatments. Our company offers a range of disease modeling services for NVG that enable researchers to study the disease in a controlled and reproducible manner. Our NVG animal models provide an excellent and valuable resource for researchers looking to advance their understanding of this serious ocular condition. With our expertise and state-of-the-art facilities, we are well-positioned to support a wide range of research projects aimed at developing new therapies and improving patient outcomes. Background NVG is a rare, aggressive, and blinding secondary glaucoma. Primary diseases include central venous obstruction (CRVO), diabetic retinopathy (DR), old retinal detachment, and ocular tumors. The typical clinical features are iris neovascularization and elevation of intraocular pressure (IOP). In recent years, there have been many experimental studies on NVG, and some new treatment methods have emerged. These therapies include pan-retinal photocoagulation (PRP), anti-VEGF therapy, drug therapy, and surgical treatment. NVG formation is a dynamic process divided into three stages: pre-glaucoma, open-angle glaucoma, and angle-closure glaucoma. Without treatment, neovascularization of the iris (NVI) may further develop angle closure, resulting in elevated IOP and secondary NVG. At present, one of the difficulties in NVG research is the lack of ideal animal models, and the key to NVG models lies in the establishment of NVI models.

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